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November 18, 2021

CBD For Anxiety, Does it Work?

Americans are experiencing and increased amount of anxiety and even more so since the global pandemic of 2020. Self care is a must to begin to alleviate anxiety. CBD, also know as cannabidiol, has been shown to be promising for anxiety. CBD does not contain THC. View some of the results of recent studies of CBD on anxiety.

cbd anxiety

Can CBD Be Used for Anxiety?

According to the National Alliance on Mental Illness, anxiety disorders rank among the most common mental health concerns in the United States and around the world. In the US alone, anxiety affects more than 40 million adults. Worldwide data is even worse, with nearly 245 million people (4% of the world’s population) suffering from various anxiety disorders ranging from mildly stressful to downright debilitating.

While traditional pharmaceutical and lifestyle changes can (and sometimes do) offer relief, for some, harsh and expensive pharmaceuticals with lasting side effects aren’t the best option.

This has led millions around the world to seek out natural therapies and remedies in search of effective ways to manage anxiety, one of which has been CBD (cannabidiol).

IMPORTANT DISCLAIMER: We cannot advocate nor tell you to use CBD for any particular ailment you may be experiencing. Nothing in this guide is meant to be construed as medical advice, and the CBD mentioned in this guide is not meant to diagnose, prevent or treat any medical condition. If you suffer from anxiety, please see a doctor. Similarly, if you are thinking about trying CBD for anxiety, always discuss this with your physician first.

Now the mandatory legal disclaimer is out of the way, we’d like to take you on a deep dive into what the clinical studies and scientific research says about the CBD’s potential as a therapeutic aid for managing anxiety - it looks really, really promising.

Scientific Studies and Clinical Research on the Use of CBD for Anxiety

The Journal of Neurotherapeutics (2015)

Anxiety and fear are adaptive responses that all humans experience when presented with perceived threats, however, persistent fear, stress, worry and anxiety can lead to disability and a significantly lower quality of life.

According to scientists, CBD possesses a wide range of therapeutic properties ranging from anti-inflammatory and analgesic (pain-relieving), to neuroprotective and anxiety modulating.

A look at studies on CBD for anxiety demonstrated that results were dose-dependent, with low and high doses largely ineffective, while moderate doses seemed effective.

Summary of Findings

“Preclinical evidence conclusively demonstrates CBD’s efficacy in reducing anxiety behaviors relevant to multiple disorders, including PTSD, GAD, PD, OCD, and SAD, with a notable lack of anxiogenic effects.”

The researchers also note that they saw minimal sedative effects and that CBD has an excellent safety profile.

Neurotherapeutics. 2015 Oct; 12(4): 825–836.

Published online 2015 Sep 4. doi: 10.1007/s13311-015-0387-1

Frontiers In Psychology Journal (2019)

This study looked at evaluating the efficacy of CBD to treat teenagers diagnosed with social anxiety disorder. Participants ranged in age from 18-19. Each was given a daily dose of 300mg CBD or a placebo (double-blind) for 4 weeks.

Summary of Findings

Anxiety as measured by TWO separate means of evaluation was significantly reduced in the CBD group.

Front. Psychol., 08 November 2019 |

Journal of Cannabis and Cannabis Research (2020)

This study sought to conduct a meta-analysis of existing clinical research on humans using CBD for anxiety.

Summary of Findings

Evaluation of clinical research and studies revealed that preliminary evidence of using CBD for anxiety suggests that it may be an effective therapeutic aid or treatment. The authors note that more research is necessary to substantiate any type of claim.

Frontiers In Immunology Journal (2018)

This study’s aim was to evaluate and discuss the developments and advances in the experimental use of cannabidiol (CBD) in neuropsychiatry. It specifically looked at therapeutic applications of CBD to evaluate its potential use as a treatment for a range of maladies.

Summary of Findings

The researchers determined that the data clearly demonstrated CBD’s anxiolytic (anti-anxiety) properties, as well as neuroprotective and antipsychotic properties.

Front Immunol. 2018; 9: 2009.

Published online 2018 Sep 21. doi: 10.3389/fimmu.2018.02009

Journal of Alzheimer’s Disease (2014)

This study looked at evaluating the potential of CBD to reverse cognitive decline attributable to Alzheimer’s.

Summary of Findings

Researchers found that CBD was able to turn back the clock on cognitive impairment (to a degree), improving object recognition, memory and social recognition while having a favorable impact on anxiety.

Journal: Journal of Alzheimer's Disease, vol. 42, no. 4, pp. 1383-1396, 2014

BJGP Open Journal (Royal College of General Practitioners, 2020)

The aim of this study was to review the association of CBD use with self-reported improvements in quality of life measurements. Four hundred patients entered the study.

Summary of Findings

Those patients using CBD were found to have achieved significant quality of life improvements, specifically in the areas of mental health symptoms (including anxiety and depression). Other positive side effects noted included better appetite and improved sleep. No major adverse effects were reported.

BJGP Open. 2020 Apr; 4(1): bjgpopen20X101010.

Published online 2020 Feb 5. doi: 10.3399/bjgpopen20X101010

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Cannabidiol (CBD)

Cabbabidiol is one of several cannabinoids found in the Cannabis sativa plant, that may help treat anxiety and various other conditions.

Hemp Oil

Hemp Oil contains approximately 12–18% cannabidiol, a nonintoxicating compound in C. Sativa. - (Medical News Today, March 2021)

The effects of orally administered CBD such as oils, edibles, or capsules, begin working within 30 minutes to 2 hours. - (Medical News Today, August 2020)

Hemp-derived CBD

Products are legal in all 50 states, as long as they contain no more than 0.3% THC. - (Food and Drug Administration, 2020)

  • 33% of American adults have used CBD once or more. - (SingleCare, 2020)
  • 49% of the Americans who use CBD, 49% of CDB use it for anxiety - (SingleCare, 2020)
  • 19.1% of adults in the U.S. experienced an anxiety disorder in 2019.

Why is it important to have a CBD Certificate of Analysis?

A certificate of analysis, or COA, is one of the most important factors to consider when purchasing a CBD product. - (Medical News Today June 2020)

Research published in the Journal of the American Medical Association shows that around 40% of CBD
products purchased online do not contain as much of the compound as printed on the labels. - Forbes October 2018

Most of the tested products contained levels of THC sufficient to cause serious psychoactive effects. - Readers Digest April 2021

80% Improvement in CBD Study

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A study in 2019 used CBD to treat people who were struggling with anxiety and sleep. Almost 80% of people’s anxiety improved.

Researchers found that 300-600mg of CBD significantly reduced anxiety symptoms in 57 adult males in a 2019 study. - (Medical News Today, August 2020)


The researchers found that an oral dose of 300 mg, administered 90 minutes before the test, was enough to significantly reduce the speakers’ anxiety. - (Healthline April 2020)

Overall, existing preclinical evidence strongly supports the potential of CBD as a treatment for anxiety disorders. -

In 2011, a study researched CBD’s effects on people with SAD. Participants were given an oral dose of 400 milligrams (mg) of CBD or a placebo. Those who received CBD experienced overall reduced anxiety levels. - (Healthline April 2020)

Assessing the effect of hemp oil on 72 people with an anxiety or sleep disorder, researchers found it reduced anxiety in 79.2 of the study participants - (Medical News Today, March 2021)

Evidence from human studies strongly supports the potential for CBD treatment for anxiety disorders: at oral doses ranging from 300 to 600 mg. -

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This product is not for use by or sale to persons under the age of 18. The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice. PLEASE NOTE: Zero THC is defined as (0.0%) no detectable THC, as supported by our lab testing.

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